By: Teleah Grand DVM, CVA, CVCH, CVFT, CVTP
Vaccine titers have become an increasingly popular topic among pet owners. It would be nice to know that a vaccine does not have to be administered, because the pet already has immunity. While vaccine titers measure a level of antibody response present in a pet’s system against disease, it is not the whole picture.
Vaccine Titers Do Not Tell the Whole Story.
Vaccine titers are a possibility that your pet is protected, but a positive vaccine titer does not guarantee that they ARE protected. For more information please see a blog by Dr Scott Weese DVM, DVSc Guelph, Dipl ACVIM:
https://www.wormsandgermsblog.com/2022/11/articles/animals/cats/pet-vaccination-questions-part-5-titres/. In addition, a negative vaccination titer does not mean that your pet is NOT protected against a disease. The immune system is complicated, and vaccine titers only measure one part of it.
In addition, tests are fallible. False positives and false negatives are a reality.
Clear as mud, right? I get it. I wish vaccine titers were more reliable. But they are not.
Vaccine Titers Are Not Effective for All Diseases
The only vaccine titers available are for canine distemper, canine parvovirus, canine rabies, and feline panleukopenia. All the other diseases we vaccinate for such as leptospirosis, canine adenovirus, bordetella, feline calici and rhinotracheitis virus do not produce long-lasting or measurable antibody responses. Therefore, we don’t have any way to test for immunity.
Vaccine Titers Can Either Be Costly and Time Consuming, or Less Expensive and Unreliable
Remember, how I mentioned that false positives and false negatives are a reality? Most tests have some measures of sensitivity and specificity. Sensitivity and specificity identify the amount of false positive and false negatives that a test can result in. Currently, the best available vaccine titers are serial dilutions performed through either the University of Kansas or University of Cornell, can take 4-6 weeks for a result, and they are expensive.
All other point of care tests (in clinic type tests) are either less sensitive or less specific and you run the high risk of a result that is not reliable. Point of care tests tend to be less expensive than a serial dilution test, however, they are much less reliable. Unfortunately, there is no perfect test.
Vaccine Titers May Not Satisfy Legal Requirements
In the state of Texas, a positive Rabies titer is not considered proof of vaccination. Your pet will be considered “unvaccinated”, unless they have an actual, up to date, rabies vaccine administered by a veterinarian. The laws must be this strict due to potential zoonotic (spread from animal to human disease) and public health risks associate with rabies.
In addition, your pet’s “unvaccinated” status may prevent them from being accepted into boarding, grooming, veterinary facilities and prevent them from traveling.
Situations Where Vaccine Titers are Recommended
Vaccination titers are recommended in pets who have or are in remission with an autoimmune disease (and those need to have had at least one vaccine beyond the age of 16-20 weeks of age). Where the pet’s immune system has already shown itself to be unpredictable and unstable. Or if your pet has had a severe (and I mean life threatening) allergic reaction to a vaccine. It is the only way of being able to tell if that pet has the possibility (not actual, just the possibility) of immunity. Vaccinating these pets means we take a higher risk of them getting sick again, or possibly dying. At no time is a vaccine titer recommended in a puppy or kitten under the age of 20 weeks, or a pet who has never been vaccinated.
Situations Where Vaccines are Recommended
All other pets, especially puppies and kittens, should be vaccinated. See our blog https://accstonebridgeranch.com/vaccines-the-good-the-questionable-and-the-myths/
Why We Recommend Vaccines
I understand that vaccinations come with some risk. The biggest question to ask is if the benefit outweighs the risk.
My dog, Bucky, (love of my life) is THAT dog that developed a life-threatening autoimmune disease at the age of 10 months. (BTW, he got his full puppy series vaccinations) Did a vaccine cause his disease? Probably not. Could a vaccine pull him out of remission? The risk is high that injectable vaccines could. Should we vaccinate? (I am discussing injectable vaccines only. Oral or intranasal vaccines are inherently without risk) I am not comfortable using any injectable vaccines such as DHPP, Lepto, or Rabies for Bucky. I recognize and acknowledge what limitations I am giving him, and what could happen (both medically and legally) if I do not vaccinate him. But my risk outweighs any benefit at this point in time.
I honestly wish he wasn’t in the minority of pets that should use vaccine titers. But he is. And when I ran titers, they were negative. Is he immune? Is he not? I don’t know. It’s scary, every day, to know what risks I am taking with Bucky not being vaccinated and having negative titers. Rock, meet hard place. But I’m still not taking that risk with him. Today. That could change in the future…
Natural Immunity and Why Nature is Not Always Kind
Let’s put aside the cost. Let’s put aside the fact that vaccine titers may not measure actual immunity (or the lack of such). Let’s put aside legal requirements. Let’s look at natural immunity.
I get questioned frequently that isn’t it better to support immunity naturally? Isn’t it better to support the pet’s immune system and let a pet develop natural immunity on its own rather than risk a possible adverse event from a vaccine? The simple answer is no.
The infectious diseases we want to prevent are serious, life threatening and possibly zoonotic (can be transferred to humans) diseases. THESE DISEASES ARE NATURAL! Very natural. And they can cause severe illness or death in your pet. You must realize that just because your unvaccinated pet has not come down with a disease yet, does not mean they won’t, if unvaccinated. You are taking a risk. Just like I am with my dog. Only I don’t really have a choice.
A few years ago, in 2022, there were reports of a new mystery illness that was affecting and killing adult dogs and puppies in Michigan. It turned out to be just an outbreak of parvovirus. All dogs affected were improperly vaccinated or unvaccinated. Those deaths and illnesses were preventable. We should not throw out centuries of medicine and studies just because prevention isn’t “natural”. If that were so, you’d have to give up cars, stores, homes, telephones, and all the things that we use to prevent nature from making our lives miserable.
We can protect your pet safely and with minimal risks. A vaccine is the safest, most effective way of doing that in otherwise healthy pets. A titer is not, but may be the best way we have available, to a small subset of patients to whom the vaccine is a higher risk. I understand that there is conflicting information out there about vaccines and their safety. To be fair, I agree with some, and disagree with others. My goal as an integrative veterinarian is to keep your pet as safe as possible from all the things that can hurt or even kill them, and sometimes that means taking a risk. Personally, I think vaccines carry a very small risk with a very large benefit.
Our Promise to You…
Something my father told me years ago really stuck with me. As he gave me my first car, he said, “Please, buckle your seat belt. I would never forgive myself if something happened to you in something I gave you.” To this day, and far beyond the car he gave me, I still buckle my seat belt, because while a seat belt poses a small risk of injury when buckled, it may prevent a more serious injury or death in the case of a serious accident. As a veterinarian, I sometimes have to recommend taking a small risk of injury to prevent a more serious or life threatening disease if your pet is exposed to something life threatening. The most frustrating and heartbreaking cases I see are the ones that could have been prevented.
My promise to you is that we will carefully and thoughtfully educate you and make recommendations that are in the best interest of your pet. We will provide you with guidance and recommendations that are progressive and take into consideration every risk vs every benefit. (i.e. we have not been over vaccinating pets since we opened in 2002, long before 3-year intervals were considered standard).
We do our best to continually evaluate and provide vaccines that are safer and have lower risks of adverse events. We will educate you on your choices, the benefits and the risks of those choices.
We should weigh the pros and cons together, considering each pet’s unique needs, age, health status and risk factors for disease exposure and come up with a thoughtful, educated, tailored approach together. We are here show you how to buckle your pet’s seat belt…. Because if something happens to your pet that we could have prevented, we will not forgive ourselves.
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